Orochimaru - He is one of the legendary Sennin, who were taught by the fourth Hokage himself. His goal is to learn many techniques and come up with some of his own. He is considered immortal because he has a techinique where he can take one's body and use it as a tool until he wants to change, but he has to wait a few years between each exchange.

Gaara of the Desert - He was born in the desert village and his mother died at his birth. He was born with the power to control the sand and he has a demon inside of him. He has a ruthless attitude and has killed many.

Kankuro - He is in Gaara's group. He uses a doll as his weapon, which he can fully control.

Temari - She is a member of Gaara's group. She uses a giant fan as her weapon which can create gusts of wind that can cut things.

Jiroubou - He is a member of the Sound 4 which is orochimaru's elite group. He likes to eat away the enemy's chakra until they are left useless and can't fend for themself.

Kidoumaru - He is a member of the Sound 4. He has 4 arms and is spider-like. He uses his chakra to mold threads from his mouth like a spider's web.

Sakon - He is a member of the Sound 4. He has 2 heads which actually consists of 2 different people. One of his heads just sleeps until he wants to wake up, usually during a big fight. The dormant body has an ability that makes him able to join his body to another body.

Tayuya - She is a member of the Sound 4. She can call out giant monsters which she can fully control with her flute.

Kabuto - He is a healer ninja who is Orochimaru's sidekick. He was used as a spy until he was found out.

Uchiha Itachi - He is Sasuke's older brother and the strongest of the Uchiha clan. He was the one who killed all the members of the Uchiha clan and left Sasuke alone. After that, he left Konoha and joined Orochimaru with many others.